Q. 51

Which moieties of nucleosides are involved in the formation of phosphodiester linkages present in dinucleotides? What does the word di-ester in the name of linkage indicate? Which acid is involved in the formation of this linkage?

Answer :

Nucleosides are linked to phosphoric acid at 5’ carbon of the sugar moiety to form a nucleotide. To form a dinucleotide, two nucleotides are linked by phosphodiester linkage between the 5’ and 3’ carbon atom of adjacent pentose sugars. Phosphoric acid is involved in the formation of this linkage.


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