Q. 24.5( 2 Votes )

What is the role played by Renin-Angiotensin in the regulation of kidney function?

Answer :

The Juxtaglomerular (JG) apparatus has a regulatory role to play.


When there is a fall in glomerular filtration rate (GFR), they activate the JG cells to release renin which gets converted to angiotensinogen in blood to angiotensin I and further to angiotensin II. Angiotensin II, is a powerful vasoconstrictor that increases the GFR.


Angiotensin II is also responsible for activating the adrenal cortex to release Aldosterone which causes reabsorption of Na+ and water from the distal parts of the tubule leading to an increase in blood pressure and GFR.


This mechanism is known as the Renin-Angiotensin mechanism that regulates the kidney function.


The juxtaglomerular apparatus is a structure formed by the distal convoluted tubule and the glomerular afferent arteriole.



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