Answer :
Adenosine deaminase also known as ADA enzyme.
ADA enzyme is vital for proper functioning of the immune system.
The ADA enzyme deficiency is mainly caused due to deletion of ADA gene. That is ADA enzyme deficiency is caused due to mutation in ADA gene.
The adenosine deaminase enzyme deficiency is a genetic disorder.
This deficiency is autosomal recessive disorder mainly found in children very rarely.
ADA enzyme acts upon Deoxyadenosine, which is toxic substance produced in the body. The Deoxyadenosine kill the T and B lymphocytes which are immunogenic cells. So the patient with ADA enzyme deficiency lacks resistance to fight against pathogens.
The ADA enzyme deficiency in turn causes SCID (Severe Combined Immune Deficiency) in infants.
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