Answer :

1. In the above case as replication could take place in the presence of radioactive deoxynucleotides precursors in E. coli that was a mutant for DNA ligase, Okazaki fragments would not be joined on the lagging strand.

2. Hence, on the leading strand high molecular weight fragments would form.

3. On the lagging strand low molecular weight fragments would form.

4. Which concludes option ‘a’ is correct.

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