Answer :

The enzyme that helps to join DNA fragments is DNA ligase.

Solution: During lagging strand synthesis in DNA replication, DNA ligase is responsible for joining the Okazaki fragments in the lagging strand after replacing the RNA primers.


The mechanism of DNA ligase is as follows:


It forms two covalent phosphodiester bonds between the 3' hydroxyl ends of one of the nucleotides and with the 5' phosphate end of another nucleotide. This process requires two ATP molecules for the formation of each phosphodiester bond.



Rate this question :

How useful is this solution?
We strive to provide quality solutions. Please rate us to serve you better.
Try our Mini CourseMaster Important Topics in 7 DaysLearn from IITians, NITians, Doctors & Academic Experts
Dedicated counsellor for each student
24X7 Doubt Resolution
Daily Report Card
Detailed Performance Evaluation
caricature
view all courses