Q. 14

Mention the substances that exit from the tubules in order to maintain a concentration gradient in the medullary interstitium.

Answer :

The substances that exit from the tubules in order to maintain a concentration gradient in the medullary interstitium are urea and sodium chloride.

Urea is a breakdown protein of amino acid metabolism which is freely filtered at the glomerulus. The high osmolarity of the renal medullary interstitium provides a concentration gradient needed for water reabsorption to occur.



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