Q. 155.0( 1 Vote )

It is said, that the harmful alleles get eliminated from population over a period of time, yet sickle cell anaemia is persisting in human population. Why?

Answer :

Sickle cell anaemia is persisting in human population. It is a good disease example of a balancing selection, with affected individuals carrying mutations in both the parental and maternal inherited haemoglobin gene. As a result their red blood cells are less efficient in carrying oxygen throughout the body. But there is a biological advantage associated with sickle cell anaemia that the patients are better protected against malaria. This resistance offered against malaria disease could be the reason for the harmful alleles of sickle cell anaemia to persist in human population despite of the elimination of harmful genes over time.


Rate this question :

How useful is this solution?
We strive to provide quality solutions. Please rate us to serve you better.
Related Videos
How to solve applied questions based on Mendel's law of inheritance46 mins
Everything About Genetic DisordersFREE Class
Interactive Quiz on Principles of Inheritance and Variation33 mins
Pedigree chart58 mins
Medelian disorder series: Thalassemia, Sickle cell anaemia & Phenylketonuria60 mins
How to solve questions of pedigree chart49 mins
Interactive Quiz on Molecular basis of Inheritance-0234 mins
Meselson and Stahl experiment49 mins
NEET 2021 | Transcription - An important Topic62 mins
DNA Fingerprinting42 mins
Try our Mini CourseMaster Important Topics in 7 DaysLearn from IITians, NITians, Doctors & Academic Experts
Dedicated counsellor for each student
24X7 Doubt Resolution
Daily Report Card
Detailed Performance Evaluation
view all courses