Q. 3 G3.6( 14 Votes )

Account for the f

Answer :

Gabriel phthalimide synthesis is a very convenient method for the preparation of pure aliphatic amines ( especially primary amines) Phthalimide on treatment with ethanolic KOH gives potassium phthalimide which on heating with a suitable alkyl hallide gives N-substituted phthalimides. These upon susbsequent hydrolysis with dil.HCl under pressure or with alkali gives primary amines.


Step 1: Phthalimide is treated with KOH to form potassium phthalimide



Step 2: Potassium phthalimde is treated with suitable alkyl hallide to form N-substituted phthalimides.



Step 3: N-substituted phthalimides undergoes hydrolysis in the prsence of dil HCl or with alkali(NaOH) to give primary amines.



Overall reaction:



Gabriel phthalimide synthesis results in the formation of primary(1° amine) only. Secondary or tertiary amines are not formed through this synthesis. Hence, Gabriel phthalimide synthesis preferred for the formation of primary amines only.


Rate this question :

How useful is this solution?
We strive to provide quality solutions. Please rate us to serve you better.
Try our Mini CourseMaster Important Topics in 7 DaysLearn from IITians, NITians, Doctors & Academic Experts
Dedicated counsellor for each student
24X7 Doubt Resolution
Daily Report Card
Detailed Performance Evaluation
caricature
view all courses
RELATED QUESTIONS :

(a) Write the reaChemistry - Board Papers