Q. 105.0( 2 Votes )

ELISA technique is based on the principles of antigen-antibody interaction. Can this techique be used in the molecular diagnosis of a genetic disorder, such as phenyketonuria?

Answer :

Phenylketonuria is an in born error which occurs due to absence of enzyme required for the conversion of tyrosine into phenylalanine.

Yes, ELISA can be used to detect the presence of phenylketonuria. The patient in which enzyme-antibody complex enzyme is absent will give negative test, and would prove the absence of enzyme. Hence positive test for phenylketonuria.


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