Q. 24.7( 3 Votes )
C-peptide of human insulin is:
A. A part of mature insulin molecule
B. Responsible for formation of disulphide bridges
C. Removed during maturation of pro-insulin to insulin
D. Responsible for its biological activity.
C-peptide of human insulin is a component used in the production of human insulin by recombinant DNA technology. The C-peptide is a short protein chain which is used to connect the A and B – peptide chains which are present in E.coli. After connecting the A and B peptide chains with disulphide bonds the C-peptide is removed during maturation of pro-insulin to insulin.
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Explain how Eli Lilly, an American company produced insulin by recombinant DNA technology.Biology - Board Papers