Q. 7 E4.5( 10 Votes )

Write short notes on

Ammonolysis

Answer :


When an alkyl or benzyl hallide allowed to react with an ethanolic solution of ammonia, it undergoes nucleophilic substitution reaction in which the halogen atom is replaced by amino (-NH2 group) The process of cleavage of the C-X bond by ammonia is called Ammonolysis.


When this substituted ammonium salt is treated with a strong base such as sodium hydroxide, amine is formed.



Though primary amine is produced as the major product, this process produces a mixture of primary, secondary and tertiary amines and also quaternary ammonium salts as shown below:



This method cannot be used for the preparation of arylamines (aniline) since aryl halides are much less reactive than alkyl halides towards nucleophilic substitution reaction.


Note: Nucleophilic substitution reaction is the reaction of an electron pair donor (Nu, the nucleophile) with the electron pair acceptor (the electrophile) For example:



Rate this question :

How useful is this solution?
We strive to provide quality solutions. Please rate us to serve you better.
Related Videos
Preparation of Amines45 mins
General introduction of Amines54 mins
Chemical reaction of Amines45 mins
Recap of Amines | A Thorough Revision46 mins
Try our Mini CourseMaster Important Topics in 7 DaysLearn from IITians, NITians, Doctors & Academic Experts
Dedicated counsellor for each student
24X7 Doubt Resolution
Daily Report Card
Detailed Performance Evaluation
view all courses