(b): Yeast ( Saccharomyces cerevisiae) is used to produce hepatitis-b vaccine using rDNA technology.
Yeast derived vaccine was safe and was equally immunogenic and protective against hepatitis-b as plasma derived vaccine.
Human hepatitis -b virus vaccine was prepared using antigen produced by recombinant technology in Yeast.
The highly purified antigen had the correct amino acid sequence and assumed the appropriate conformational structure to present the immunologic determinants that are needed to stimulate an appropriate immune response.
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